Dextran producing lactic acid bacteria was isolated from the pulp of pummelo (Citrus maxima) and was phenotypically and biochemically characterized. Its was identified to be Weissella cibaria with the strain name given as ...
Bacterial L-asparaginase has been widely used as a therapeutic agent in the treatment of certain kinds of cancer, mainly in treatment of acute lymphoblastic leukemia. Moreover, L-asparaginase is used in food industry for ...
Cutinase has some vital properties of lipase and esterase. Because of its unique nature, it has potential of being an industrially important enzyme. Some of the useful applications of cutinase include hydrolysis of fats ...
The thermophilic bacterium Clostridium thermocellum contains multienzyme complex called cellulosome which is known to degrade recalcitrant substrates. In this study one of the cellulosomal enzymes, β-1,3-glucanase (CtLam81A) ...
Dextrans are a class of homopolysaccharides composed of D-(1D6) glycosidic linkages in the main chains and D-(1D2), D-(1D3) and D-(1D4) branched glycosidic linkages. Dextrans may be linear or branched, with variable degree ...
Plant cell wall were composed of polymers for example cellulose, various hemicellulose and lignin and can be converted into alcohol that can be served as renewable source of energy. Saccharification of cellulose (major ...
Protein-RNA recognition plays major role in biology, viz., charging tRNA by synthetase, structural stability of ribosome, stop-codon recognition by translation factors in the ribosome, viral-RNA recognition by innate immune ...
Cancer cells are known to lack regulation of cell proliferation due to the aberrant behavior of a myriad of signaling pathways. One such pathway is the Wnt signal cascade, which is one of the multiple facets responsible ...
Toxicity of Bacterial toxins , like diphtheria tocin has been widely utilized to create therapeutic agents that can kill target cells. For example, Immunotoxins have been developed by fusing antibodies to diphtheria toxin. ...
Human Cripto-1 (CR-1) is an oncofetal protein. It is a modulator of embryogenesis and oncogenesis. It is involved in multiple signaling pathways, which are essential for cellular transformation, metastasis and angiogenesis. ...
Bone marrow niche is composed of cellular and non-cellular compartments. Cellular environment includes hematopoietic stem cells (HSCs), non-hematopoietic stem cells and their derivatives. HSCs maintain the blood cell ...
Proteins are the most abundant intracellular macromolecules which perform a diverse range of functions within the living cell. They are known to absorb in the UV region of the electromagnetic spectrum owing to the presence ...
Cancer cells acquiring resistance to chemotherapeutic drugs remain the most serious obstacle to the development of an efficient anti-cancer therapy. Overexpression of ABC transporter genes is associated with active expulsion ...
The skin, also known as protective barrier, is the largest organ of our body that defends the body against external environment, pathogens and mechanical disturbances. Cutaneous wounds, often caused by trauma or wound ...
Low back pain (LBP) is an important clinical and socio-economic condition affecting the population indiscriminately across the globe. Intervertebral disc (IVD) degeneration is the major cause of LBP. The conventional ...
This thesis deals with silk biopolymer based approaches for islet macroencapsulation to overcome the limitations associated with conventional treatment modalities for Type 1 diabetes. These approaches overcome host ...
The proteins we observe in nature have evolved through selective pressure to do certain specific functions such as catalyzing and regulating biochemical reactions, transporting molecules that permit cells to grow and ...
The ability to direct peptide self-assembly opens up important avenues to construct a rich variety of molecular assemblies with novel functions. Besides, directing the folding and inhibiting aggregation may be an effective ...