Medicinal plants are indispensible to human health. From times immemorial, the therapeutic benefits offered by these plants have been exploited by the common people and medical professionals alike. This is the reason why ...
Skin, the largest organ of human body provides physical protection against biological, mechanical, thermal and chemical assaults. However, chronic exposure of skin to ultraviolet (UV) radiations depletes enzymatic and ...
Bacterial infections in the gastrointestinal tract is a critical healthcare issue. In this context, the use of antibioticmediated therapy to achieve pathogen clearance from the gastrointestinal milieu is counterproductive ...
The macrophages express various receptors on their surface to assist in the innate immune response. The scavenger receptors expressed on the macrophage cell surface are involved in a broad range of functions, including ...
Intrinsically Disordered Proteins (IDPs) do not have any well-defined stable secondary or tertiary structure under the physiological conditions. Regardless of lacking stable structure, IDPs have several structural and ...
Despite the superior renewable source of biodiesel, microalgae cultivation technology has been facing commercial challenges such as inefficient photobioreactor (PBR) design and low biomass yielding open pond practices. The ...
Human interferon gamma (hIFN-γ) is a pleiotropic cytokine that is produced by natural killer cells and T lymphocytes. hIFN-γ plays an key role in communicating innate and acquired immune systems during bacterial and viral ...
Prodrig gene therapy , commonly known as suicide gene therapy, provides a selective approach to eradicate tumer cells. Development of efficient suicide gene therapy vectors to improve the therapeutic efficacy is the main ...
Dextran producing lactic acid bacteria was isolated from the pulp of pummelo (Citrus maxima) and was phenotypically and biochemically characterized. Its was identified to be Weissella cibaria with the strain name given as ...
Bacterial L-asparaginase has been widely used as a therapeutic agent in the treatment of certain kinds of cancer, mainly in treatment of acute lymphoblastic leukemia. Moreover, L-asparaginase is used in food industry for ...
Cutinase has some vital properties of lipase and esterase. Because of its unique nature, it has potential of being an industrially important enzyme. Some of the useful applications of cutinase include hydrolysis of fats ...
The thermophilic bacterium Clostridium thermocellum contains multienzyme complex called cellulosome which is known to degrade recalcitrant substrates. In this study one of the cellulosomal enzymes, β-1,3-glucanase (CtLam81A) ...
Dextrans are a class of homopolysaccharides composed of D-(1D6) glycosidic linkages in the main chains and D-(1D2), D-(1D3) and D-(1D4) branched glycosidic linkages. Dextrans may be linear or branched, with variable degree ...
Plant cell wall were composed of polymers for example cellulose, various hemicellulose and lignin and can be converted into alcohol that can be served as renewable source of energy. Saccharification of cellulose (major ...
Protein-RNA recognition plays major role in biology, viz., charging tRNA by synthetase, structural stability of ribosome, stop-codon recognition by translation factors in the ribosome, viral-RNA recognition by innate immune ...
Cancer cells are known to lack regulation of cell proliferation due to the aberrant behavior of a myriad of signaling pathways. One such pathway is the Wnt signal cascade, which is one of the multiple facets responsible ...
Toxicity of Bacterial toxins , like diphtheria tocin has been widely utilized to create therapeutic agents that can kill target cells. For example, Immunotoxins have been developed by fusing antibodies to diphtheria toxin. ...
Human Cripto-1 (CR-1) is an oncofetal protein. It is a modulator of embryogenesis and oncogenesis. It is involved in multiple signaling pathways, which are essential for cellular transformation, metastasis and angiogenesis. ...