Synthesis of Oxygen, Nitrogen and Sulfur Heterocycles

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dc.contributor.author Borthakur, Upasana
dc.date.accessioned 2021-08-24T10:39:06Z
dc.date.available 2021-08-24T10:39:06Z
dc.date.issued 2020
dc.identifier.other ROLL NO.146122019
dc.identifier.uri http://gyan.iitg.ernet.in/handle/123456789/1932
dc.description Supervisor: Anil kumar Saikia en_US
dc.description.abstract The contents of the thesis have been divided into five chapters based on the results gathered by various experiment work performed during the complete course of the research period. The chapter 1 presents an introduction to oxygen, nitrogen and sulfur containing heterocyclic compounds, their biological importance and different literature methods for their synthesis. Chapter 2 describes synthesis of tetrahydro-1H-indeno[1,2-b]pyridine via cascade cyclization and Friedel-Crafts reaction. The methodology has been used for the total synthesis of antidepressant agent (+)-5-phenyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine. In Chapter 3, use of vinylsilanes in diastereo- and regio-selective synthesis of dihydropyrans via oxonium-ene cyclization reaction has been reported. Chapter 4 is about the use of vinylsilanes in highly diastereo- and regio-selective synthesis of 1,10b-dihydropyrido[2,1-a]isoindol-6(4H)-one via iminium–ene cyclization reaction. Chapter 5 deals with bismuth triflate catalyzed highly diastereoselective synthesis of substituted tetrahydrothiophene via tandem isomerization, Michael and aldol reactions. en_US
dc.language.iso en en_US
dc.relation.ispartofseries TH-2486;
dc.subject CHEMISTRY en_US
dc.title Synthesis of Oxygen, Nitrogen and Sulfur Heterocycles en_US
dc.type Thesis en_US


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